abstract：:Knife cuts in the frontal plane separating the anterior part of the caudate-putamen from the globus pallidus resulted in marked decreases in substances P levels in the reticular part of the substantia nigra. More caudal knife cuts were required in order to effect maximal decreases in nigral glutamic acid decarboxylase...

journal_title：Brain research

authors： Brownstein MJ,Mroz EA,Tappaz ML,Leeman SE

更新日期：1977-10-28 00:00:00

abstract：:This study shows that permanent cell lines can be established from rat and mouse brain by direct tissue culture methodology without the aid of exogenous chemical or viral transforming agents. These cells were derived from specific areas of the brain, such as the cerebellum and hippocampus, at chosen times during fetal...

journal_title：Brain research

authors： Bulloch K,Stallcup WB,Cohn M

更新日期：1977-10-21 00:00:00

abstract：:Horseradish peroxidase (HRP) injected into developing limb buds of Xenopus laevis tadpoles is carried by retrograde axonal transport to the somata of motoneurones in the ventral horn. Small injection of 10% HRP were found to remain well localised to specified sites in the limb bud. Two types of labelled cells were fou...

journal_title：Brain research

authors： Lamb AH

更新日期：1977-10-07 00:00:00

abstract：:Antibody has been prepared to purified neurofilament protein extracted from calf brain. This antibody crossreacts with brain and nerve extracts from all mammals tested but fails to crossreact with frog, cod and chicken nerve extracts. Thus the serologic homology of these neurofilament proteins appears to be restricted...

journal_title：Brain research

authors： Davison PF,Hong BS

更新日期：1977-10-07 00:00:00

abstract：:The opposing actions of diphenylhydantoin (DPH) and calcium on the level of [32P]phosphate incorporation into particular rat and human brain proteins have been demonstrated in this study by employing the techniques of acrylamide gel electrophoresis and autoradiography. In the presence of calcium several brain proteins...

journal_title：Brain research

authors： DeLorenzo RJ

更新日期：1977-09-23 00:00:00

abstract：:In anaesthetized, spontaneously breathing cats and dogs, extracellular recordings were made of the spontaneous activities of 28 single neurones with cardiac rhythm. It was confirmed by histological examination that the neurones were situated in the mediodorsal portion of the nucleus of the solitary tract. Different di...

journal_title：Brain research

authors： Stroh-Werz M,Langhorst P,Camerer H

更新日期：1977-09-09 00:00:00

abstract：:Unilateral nigrostriatal lesions were performed in rats by punctate injection of 6-hydroxydopamine. Lesioned animals exhibited anorexia and weight loss for 7-11 days after surgery. These animals then displayed normal rate of weight gain. However, there was a chronic depression of body weight in the lesioned animals re...

journal_title：Brain research

authors： Baez LA,Ahlskog JE,Randall PK

更新日期：1977-09-02 00:00:00

abstract：:An autoradiographic determination of the time of origin of the lateral motor columns (LMC) of the chick embryo has been made. The first motor neurons of the brachial LMC are born at stage 15; the earliest birthdates of lumbar LMC neurons are at stage 17. At least 95% of the motor neurons of both brachial and lumbar co...

journal_title：Brain research

authors： Hollyday M,Hamburger V

更新日期：1977-08-26 00:00:00

abstract：:Unilateral olfactory nerve section was performed in the mouse. Three biochemical markers of the olfactory chemoreceptor neurons: carnosine, carnosine synthetase activity and the olfactory marker protein, were measured in the olfactory bulb and epithelium. Parallel observations were made by light microscopy as well as ...

journal_title：Brain research

authors： Harding J,Graziadei PP,Monti Graziadei GA,Margolis FL

更新日期：1977-08-19 00:00:00

abstract：:Amino acid uptake by slices of brain is greatly diminished by incubation of the slices in glucose-free media. Uptake can be restored by the addition of a number of substrates, e.g., lactate, citrate, or oxaloacetate. The mixture of succinate, malate, and pyruvate (SMP, 20, 5, and mM) restored amino acid uptake better ...

journal_title：Brain research

authors： Teller DN,Bana-Schwartz M,Deguzman T,Lajtha A

更新日期：1977-08-12 00:00:00

abstract：:A quantitative study of Wallerian degeneration was carried out on teased fibres. The breakdown into ovoids was used as the criterion of degeneration. The fragmentation of fibres begins near the point of nerve interrruption and spreads along the unbranched parts of axons at velocities correlated with fibre diameter and...

journal_title：Brain research

authors： Lubińska L

更新日期：1977-07-08 00:00:00

abstract：:The ontogenic development of neurophysin has not been investigated so far. To study this problem, electron microscopic immunohistochemistry was performed on ultrathin sections of the posterior pituitary of foetal and newborn rats. A concomitant appearance of secretory granules and neurophysin was first noted in the po...

journal_title：Brain research

authors： Leclerc R,Pelletier G

更新日期：1977-07-01 00:00:00

abstract：:The immunocytological study of LH-RH producing neurons was carried out on 3 newborns and 14 fetuses (from 10 to 36 weeks of age). Perikarya and fibers which were immunoreactive to anti-LH-RH IS were revealed by IF or IE in all the hypothalamus beginning with the 13th week. Important variations in neurons staining may ...

journal_title：Brain research

authors： Bugnon C,Bloch B,Fellmann D

更新日期：1977-06-10 00:00:00

abstract：:The rapid saltatory motion of intra-axonal particles detected by dark-field microscopy in myelinated axons isolated from sciatic nerves of adult Xenopus laevis was inhibited by colchicine or vinblastine at a concentration of larger than or equal to 0.1 mM. Both the predominant somatopetal transport and the somatofugal...

journal_title：Brain research

authors： Hammond GR,Smith RS

更新日期：1977-06-10 00:00:00

abstract：:A procedure has been developed for the stable long-term recording of nerve signals in unanesthetized mammals, which should have wide application in basic research on the nervous system and also in clinical areas such as the derivation of control signals for powered prostheses. Methods are fully described for construct...

journal_title：Brain research

authors： Stein RB,Nichols TR,Jhamandas J,Davis L,Charles D

更新日期：1977-06-03 00:00:00

abstract：:The effects of morphine sulfate and two benzodiazepine derivatives, chlordiazepoxide HCl and diazepam, were evaluated upon single unit activity of the amygdaloid nuclear complex and hippocampal formation in immobilized cats. All surgical procedures were performed under halothane anesthesia and all wound margins were i...

journal_title：Brain research

authors： Chou DT,Wang SC

更新日期：1977-05-13 00:00:00

abstract：:In the dorsal lateral geniculate nucleus (LGN) of the adult cat there is no evidence for translaminar sprouting of retinal axons to fill sites freed of retinal endings from the other eye. We tested the possibility that retinal axons will sprout to fill denervated retinal sites within laminae of the monkey LGN. In 4 mo...

journal_title：Brain research

authors： Stelzner DJ,Keating EG

更新日期：1977-05-06 00:00:00

abstract：:Rats were exposed to 1.3 gHz microwave energy to assess the uptake of several neutral polar substances in certain areas of the brain. A quantitative, radioactive isotope method, which uses an internal standard, was employed to measure the loss of test substances to brain tissue. Single, 20 min exposure, to either puls...

journal_title：Brain research

authors： Oscar KJ,Hawkins TD

更新日期：1977-05-06 00:00:00

abstract：:Three groups of rats, one with amygdala lesions, one with hippocampal lesions and a control group were trained on a brightness discrimination task under one of three different conditions, enhancement of the negative cue, enhancement of the positive cue or a non-enhanced condition. Animals with amygdala lesions showed ...

journal_title：Brain research

authors： Han MF,Livesey PJ

更新日期：1977-04-15 00:00:00

abstract：:The activity of the crayfish caudal photoreceptor (Ph) was studied during the application of a classical conditioning paradigm. This cell is a primary photoreceptor and, at the same time, a secondary neuron in the mechanoreceptive pathway. The electrical stimulation of afferent mechanoreceptor fibers, the analog of th...

journal_title：Brain research

authors： Roger M,Galeano C

更新日期：1977-04-01 00:00:00

abstract：:Experiments were carried out in rats to (1) elaborate upon the sepcificity of drug action in the periaqueductal gray matter (PAG), and (2) to evaluate the posible congruence of PAG sites of morphine-induced and stimulation-produced analgesis (SPA) applied at virtually identical PAG loci. It was demonstrated that the e...

journal_title：Brain research

authors： Lewis VA,Gebhart GF

更新日期：1977-03-25 00:00:00

abstract：:A study was undertaken of the possible relationship of the binding affinity of a series of anticholinergic psychotomimetic drugs to their psychopharmacological and anticholinergic effects. Binding was measured to brain homogenates and nerve endings using [3H]quinuclidinyl benzilate (QB), a highly potent psychotomimeti...

journal_title：Brain research

authors： Baumgold J,Abood LG,Aronstam R

更新日期：1977-03-25 00:00:00

abstract：:The primary olfactory cortex of mouse embryos varying in age from the 13th to the 15th day of gestation is investigated with the aid of several techniques: Nissl and Golgi preparations, autoradiography and electron microscopy. It is observed that the earliest cells to complete their migrations are diffusely scattered ...

journal_title：Brain research

authors： Derer P,Caviness VS Jr,Sidman RL

更新日期：1977-03-04 00:00:00

abstract：:Daily changes in tryptophan-5-hydroxylase (TrH) activity have been studied in six different 5-HT-containing cell groups (B3, B4, B5, B6, B7, B8,) in the brain stem of rats maintained in a regular cycle of 12 h of light and 12 h of darkness. Significant circadian alternations of TrH activity were observed in most of th...

journal_title：Brain research

authors： Kan JP,Chouvet G,Hery F,Debilly G,Mermet A,Glowinski J,Pujol JF

更新日期：1977-03-04 00:00:00

abstract：:The effects of spinal cord hemisection on protein labeling in the medulla, pons, midbrain, and cortex in the Cebus monkey were studied by measuring the uptake of [3H]lysine into the trichloroacetic acid (TCA) precipitable and non-precipitable fractions of brain. Animals were sacrificed 3, 6 or 13 days after hemisectio...

journal_title：Brain research

authors： Bernstein JJ,Wells MR

更新日期：1977-02-25 00:00:00

abstract：:The postnatal maturation of the medial preoptic area (MPOA) of male and female rats was studied by means of light and electron microscopy. In Golgi-Kopsch preparations, bi- and multipolar cells were present at birth in both sexes; the perikarya of most of these cells, as seen with the electron microscope, exhibited an...

journal_title：Brain research

authors： Reier PJ,Cullen MJ,Froelich JS,Rothchild I

更新日期：1977-02-25 00:00:00

abstract：:Afferents to th midbrain dorsal and median raphe nuclei in the rat were studied by means of the horseradish peroxidase (HRP) retrograde transport method. The HRP was given by means of a modified iontophoretic delivery technique. This technique permitted an efficient and localized deposition of a high concentration of ...

journal_title：Brain research

authors： Aghajanian GK,Wang RY

更新日期：1977-02-18 00:00:00

abstract：:The two human brain beta-galactosidases were solubilized and fractionated by Sephadex G-200 gel filtration, free from each other. Substrate specificities of the two enzymes were examined for galactosylceramide, lactosyl-[N-stearoyl]ceramide, lactosyl-[N-lignoceroyl]ceramide, galactosyl-N-acetylgalactosaminyl-[N-stearo...

journal_title：Brain research

authors： Tanaka H,Suzuki K

更新日期：1977-02-18 00:00:00

abstract：:Electrophysiological techniques and the retrograde transport of horseradish peroxidase (HRP) were used to determine the efferent projections from the caudal mediobasal hypothalamus to the amygdala. In pentobarbital anesthetized rats, the activity of 1780 mediobasal hypothalamic neurons was examined for response to sti...

journal_title：Brain research

authors： Renaud LP,Hopkins DA

更新日期：1977-02-01 00:00:00

abstract：:Bulk-isolated human and bovine oligodendroglia, practically free from myelin, have been used in attempts to elicit an autoimmune response which has been compared with acute experimental allergic encephalomyelitis (EAE). For these experiments, a total of 20 Hartley guinea pigs, 33 Lewis rats and 16 rabbits have been st...

journal_title：Brain research

authors： Raine CS,Wiśniewski HM,Iqbal K,Grundkeiqbal I,Norton WT

更新日期：1977-01-21 00:00:00

abstract：:The search for the neural substrate of a state of consciousness has led to the expectation that there may be neurons which discharge tonically and rhythmically during that state alone. We have now recorded in the cat the first evidence of neurons whose rhythmic discharge is consistent with the hypothesis of a tonicall...

journal_title：Brain research

authors： Netick A,Orem J,Dement W

更新日期：1977-01-21 00:00:00

abstract：:A quantitative double blind procedure is described to test the myelinotoxicity of cerebrospinal fluid (SSF) by using optic nerves of Xenopus tadpoles as an in vivo model of a myelinated CNS tract. Only 0.5 ml of unconcentrated CSF is needed for a test and the result is known in 5 days. Groups of 8-10 Xenopus tadpoles ...

journal_title：Brain research

authors： Tabira T,Webster HD,Wray SH

更新日期：1977-01-14 00:00:00

abstract：:(1) Spreading depression (SD) could be elicited in isolated carp retina by KCI application, the concomitants of which were similar to those described in other vertebrates. (2) The threshold for generating SD was greatly reduced by brief immersion of the retina in low ci-ringer's solutions. The properties of SD waves w...

journal_title：Brain research

authors： Higashida H,Sakakibara M,Mitarai G

更新日期：1977-01-14 00:00:00

abstract：:In a whole mount preparation of the hooded rat retina, stained with methylene blue, the ganglion cell density was counted over the retina. The density ranged from 6200-6500/sq.mm to 1000-1500/sq.mm. The area with a density higher than 6000/sq.mm was called the central area and was centered at about 1 mm (20 degrees) a...

journal_title：Brain research

authors： Fukuda Y

更新日期：1977-01-07 00:00:00

abstract：:The cisternal spinal fluid (CF), plasma, and brain stem concentrations of 6 amino acids were measured in suckling rats between birth and one months of age. Each of the amino acids studied had its distinctive maturational pattern of CF concentration. Presumably these amino acids have separate mechanisms of transport fr...

journal_title：Brain research

authors： Korobkin RK,Cutler RW

更新日期：1977-01-01 00:00:00

abstract：:Spontaneous and hypothalamically induced hippocampal rhythmical slow activity (RSA or theta) was studied acutely in rats anaesthetized with urethane or immobilized with D-tubocurarine. Systematic tracking of microelectrodes showed two foci of hippocampal RSA, one located in the basal part (stratum oriens) of CAl (mean...

journal_title：Brain research

authors： Bland BH,Whishaw IQ

更新日期：1976-12-17 00:00:00

abstract：:There have been few reports concerning facilitation and depression in sympathetic ganglia9,17,40. In the present investigation, pairs of excitatory postsynaptic potentials (EPSPs) were recorded intracellularly from bullfrog paravertebral sympathetic ganglia for an analysis of the site and mechanism responsible for the...

journal_title：Brain research

authors： Tashiro N,Gallagher JP,Nishi S

更新日期：1976-12-10 00:00:00

abstract：:Amphetamine-induced locomotion and stereotypy were concurrently evaluated in order to determine if pretreatment with para-chlorophenylalanine (PCPA) (which is reported to facilitate some of the effects of amphetamine) results in a behavioral pattern similar to the augmentation previously reported to occur with repeate...

journal_title：Brain research

authors： Segal DS

更新日期：1976-11-05 00:00:00

abstract：:Six experimental and 3 unoperated cats were trained with a go, no-go shock avoidance procedure to discriminate increases from decreases in the rate of presentation of all auditory cortex between the suprasylvian sulcus and rhinal fissure while 3 cats had bilateral auditory cortex lesions plus ablation of the cortex of...

journal_title：Brain research

authors： Cranford JL,Igarashi M,Stramler JH

更新日期：1976-10-29 00:00:00

abstract：:The studies were performed on operation material from 17- to 63-year-old patients and on fetuses at 19-23 weeks gestational age. Formaldehyde histofluorescence showed the presence of numerous perivascular adrenergic nerves around pial and intracerebral vessels, the carotid system being better supplied than the vertebr...

journal_title：Brain research

authors： Edvinsson L,Owman C,Sjöberg NO

更新日期：1976-10-22 00:00:00